2025 Indy 500 odds: Kyle Larson drops on board after qualifying 21st

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The countdown is on to the 109th Running of the Indianapolis 500. The big event takes place on FOX on May 25, and motorsports fans are diving into the betting action.

Last year’s second-place finisher, Pato O’Ward, was at the top of the oddsboard at the beginning of February at 6/1. But now, Alex Palou is in that spot. He moved to 9/2 from 5/1 since the first day of 500 qualifying and from 10/1 over the last three months.

Palou started the year off in dominant fashion, winning four of the first five races of the 2025 season.

The reigning Indy 500 champion is Josef Newgarden. He’s second on the board, shifting to 11/ from 6/1 since qualifying on Saturday.

One of the biggest moves on the board ahead of Sunday qualifying was Kyle Larson. He dropped to 18/1 from 10/1 after qualifying 21st for the race.

Will we see a repeat champion at The Brickyard in May? 

Check out the latest odds for “The Greatest Spectacle in Racing” at DraftKings Sportsbook as of May 18 before Sunday’s qualifying rounds begin.

2025 INDIANAPOLIS 500

Alex Palou: 9/2 (bet $10 to win $55 total)

Josef Newgarden: 11/2 (bet $10 to win $65 total)

Scott McLaughlin: 6/1 (bet $10 to win $70 total)

Pato O’Ward: 13/2 (bet $10 to win $75 total)

Scott Dixon: 15/2 (bet $10 to win $85 total)

Will Power: 10/1 (bet $10 to win $110 total)

Felix Rosenqvist: 18/1 (bet $10 to win $190 total)

Kyle Larson: 18/1 (bet $10 to win $190 total)

Marcus Ericsson: 20/1 (bet $10 to win $210 total)

Takuma Sato: 20/1 (bet $10 to win $210 total)

Colton Herta: 20/1 (bet $10 to win $210 total)

David Malukas: 20/1 (bet $10 to win $210 total)

Alexander Rossi: 20/1 (bet $10 to win $210 total)

Santino Ferrucci: 25/1 (bet $10 to win $260 total)

Christian Lundgaard: 25/1 (bet $10 to win $260 total)

Helio Castroneves: 30/1 (bet $10 to win $310 total)

Kyle Kirkwood: 30/1 (bet $10 to win $310 total)

Conor Daly: 30/1 (bet $10 to win $310 total)

Robert Shwartzman: 40/1 (bet $10 to win $410 total)

Ed Carpenter: 50/1 (bet $10 to win $510 total)

Rinus Veekay: 50/1 (bet $10 to win $510 total)

Graham Rahal: 50/1 (bet $10 to win $510 total)

Kyffin Simpson: 60/1 (bet $10 to win $610 total)

Marco Andretti: 70/1 (bet $10 to win $710 total)

Ryan Hunter-Reay: 70/1 (bet $10 to win $710 total)

Marcus Armstrong: 70/1 (bet $10 to win $710 total)

Devlin DeFrancesco: 80/1 (bet $10 to win $810 total) 

Sting Ray Robb: 100/1 (bet $10 to win $1,010 total)

Jack Harvey: 100/1 (bet $10 to win $1,010 total)

Louis Foster: 100/1 (bet $10 to win $1,010 total)

Christian Rasmussen: 100/1 (bet $10 to win $1,010 total)

Callum Ilott: 100/1 (bet $10 to win $1,010 total)

Nolan Siegel: 150/1 (bet $10 to win $1,510 total)

Jacob Abel: 200/1 (bet $10 to win $2,010 total)

BEST OF FOX SPORTS’ INDY 500 COVERAGE:

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